Effects of antioxidant supplementation on the aging process
summary test inserted here
Arginine Counteracts the Inhibitory Effect of IGF-1 on the Somatotroph
This article deals with feedback effects of IGF-1 on somatostatin and how this blunts the stimulus of GHRH (sermorelin). These feedback effects may account for the initial decline in IGF-1 after starting sermorelin/GHRP therapy. Perhaps these effects can be overcome by concomittant administration of arginine.
Evidence against a role for the growth hormone-releasing peptide axis in human slow-wave sleep regulation
While GHRH (sermorelin) is associated with induction of slow wave sleep, ghrelin analogs such as GHRP-2 may or may not have such an effect. The current paper speaks against a slow wave sleep inducing effect of GHRP. If the data can be generalized, then they suggest that combinations of sermorelin and GHRP need not be taken at bedtime since their ability to increase SWS may be neutralized. Thus, the combination may be used any time of day for its more objective benefits on body composition, etc.
Ghrelin promotes slow-wave sleep in humans
Because individual variation is readily observed when using products that have physiolgical rather than pharmacological effects, it is not uncommon to see reports in well respected, peer reviewed journals having opposite outcomes. In the corresponding paper, ghrelin and its analogs are reported to promote slow wave sleep, unlike the prior report from Van Cauters group.